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Homocysteine alters cerebral microvascular integrity and causes remodeling by antagonizing GABA-A receptor
High levels of homocysteine (Hcy), known as hyperhomocysteinemia (HHcy), are associated with cerebrovascular diseases, such as vascualr dementia, stroke, and Alzheimer's disease. The -amino butyric acid (GABA) is a inhibitory neurotransmitter and a ligand of GABA-A receptor. By inhibiting excit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484206/ https://ncbi.nlm.nih.gov/pubmed/22886392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-012-1425-5 |
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