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A profusion of upstream open reading frame mechanisms in polyamine-responsive translational regulation

In many eukaryotic mRNAs one or more short ‘upstream’ open reading frames, uORFs, precede the initiator of the main coding sequence. Upstream ORFs are functionally diverse as illustrated by their variety of features in polyamine pathway biosynthetic mRNAs. Their propensity to act as sensors for regu...

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Detalhes bibliográficos
Main Authors: Ivanov, Ivaylo P., Atkins, John F., Michael, Antony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811004/
https://ncbi.nlm.nih.gov/pubmed/19920120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1037
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