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A profusion of upstream open reading frame mechanisms in polyamine-responsive translational regulation

In many eukaryotic mRNAs one or more short ‘upstream’ open reading frames, uORFs, precede the initiator of the main coding sequence. Upstream ORFs are functionally diverse as illustrated by their variety of features in polyamine pathway biosynthetic mRNAs. Their propensity to act as sensors for regu...

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Hlavní autoři: Ivanov, Ivaylo P., Atkins, John F., Michael, Antony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811004/
https://ncbi.nlm.nih.gov/pubmed/19920120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1037
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