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PTEN is a tumor suppressor in CML stem cells and BCR-ABL–induced leukemias in mice

The tumor suppressor gene phosphatase and tensin homolog (PTEN) is inactivated in many human cancers. However, it is unknown whether PTEN functions as a tumor suppressor in human Philadelphia chromosome–positive leukemia that includes chronic myeloid leukemia (CML) and B-cell acute lymphoblastic leu...

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Autores principales: Peng, Cong, Chen, Yaoyu, Yang, Zhongfa, Zhang, Haojian, Osterby, Lori, Rosmarin, Alan G., Li, Shaoguang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810991/
https://ncbi.nlm.nih.gov/pubmed/19965668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-228130
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