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Inhibitory Effects of Omacetaxine on Leukemic Stem Cells and BCR-ABL-Induced Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia in Mice

Omacetaxine mepesuccinate (formerly homoharringtonine) is a molecule with a mechanism of action that is different from tyrosine kinase inhibitors and its activity in chronic myeloid leukemia (CML) seems to be independent of BCR-ABL mutation status. Using BCR-ABL-expressing myelogenous and lymphoid c...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Yaoyu, Hu, Yiguo, Michaels, Shawnya, Segal, David, Brown, Dennis, Li, Shaoguang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726272/
https://ncbi.nlm.nih.gov/pubmed/19322212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.52
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