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A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia
We have shown that Alox5 is a critical regulator of leukemia stem cells (LSCs) in a BCR-ABL–induced chronic myeloid leukemia (CML) mouse model, and we hypothesize that the Alox5 pathway represents a major molecular network that regulates LSC function. Therefore, we sought to dissect this pathway by...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138690/ https://ncbi.nlm.nih.gov/pubmed/21596859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316760 |
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