A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia

We have shown that Alox5 is a critical regulator of leukemia stem cells (LSCs) in a BCR-ABL–induced chronic myeloid leukemia (CML) mouse model, and we hypothesize that the Alox5 pathway represents a major molecular network that regulates LSC function. Therefore, we sought to dissect this pathway by...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Yaoyu, Sullivan, Con, Peng, Cong, Shan, Yi, Hu, Yiguo, Li, Dongguang, Li, Shaoguang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2011
Konular:
Myeloid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138690/
https://ncbi.nlm.nih.gov/pubmed/21596859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316760
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