A nucleated assembly mechanism of Alzheimer paired helical filaments
Alzheimer’s disease is characterized by two types of fibrous aggregates in the affected brains, the amyloid fibers (consisting of the Aβ-peptide, generating the amyloid plaques), and paired helical filaments (PHFs; made up of tau protein, forming the neurofibrillary tangles). Hence, tau protein, a h...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1998
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9861035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15712 |
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