A nucleated assembly mechanism of Alzheimer paired helical filaments

Alzheimer’s disease is characterized by two types of fibrous aggregates in the affected brains, the amyloid fibers (consisting of the Aβ-peptide, generating the amyloid plaques), and paired helical filaments (PHFs; made up of tau protein, forming the neurofibrillary tangles). Hence, tau protein, a h...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Friedhoff, P., von Bergen, M., Mandelkow, E.-M., Davies, P., Mandelkow, E.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9861035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15712
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!