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Sodium entry during action potentials of mammalian central neurons: incomplete inactivation and reduced metabolic efficiency in fast-spiking neurons

We measured the time course of sodium entry during action potentials of mouse central neurons at 37 °C to examine how efficiently sodium entry is coupled to depolarization. In cortical pyramidal neurons, sodium entry was nearly completely confined to the rising phase of the spike: only ~25% more sod...

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Detalhes bibliográficos
Main Authors: Carter, Brett C., Bean, Bruce P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810867/
https://ncbi.nlm.nih.gov/pubmed/20064395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.12.011
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