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Impact of Fast Sodium Channel Inactivation on Spike Threshold Dynamics and Synaptic Integration

Neurons spike when their membrane potential exceeds a threshold value. In central neurons, the spike threshold is not constant but depends on the stimulation. Thus, input-output properties of neurons depend both on the effect of presynaptic spikes on the membrane potential and on the dynamics of the...

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Detalhes bibliográficos
Main Authors: Platkiewicz, Jonathan, Brette, Romain
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088652/
https://ncbi.nlm.nih.gov/pubmed/21573200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001129
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