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Incomplete Inactivation and Rapid Recovery of Voltage-Dependent Sodium Channels During High-Frequency Firing in Cerebellar Purkinje Neurons

Purkinje neurons can spike very rapidly for sustained periods. We examined the cycle of sodium channel gating during high-frequency firing of Purkinje neurons, focusing on the kinetics of sodium channel inactivation and recovery during and after spikes. To analyze sodium channel availability during...

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Detalhes bibliográficos
Main Authors: Carter, Brett C., Bean, Bruce P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059179/
https://ncbi.nlm.nih.gov/pubmed/21160003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01056.2010
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