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The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin
β-Catenin-mediated Wnt signaling is essential in embryonic development and in adult tissues. Recent studies have demonstrated that Axin not only plays an important inhibitory role in coordinating β-catenin degradation, but is itself degraded by the low-density-lipoprotein receptor-related protein (L...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810718/ https://ncbi.nlm.nih.gov/pubmed/17922036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210829 |
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