The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation

The Wnt/β-catenin signaling pathway plays essential roles in embryonic development and adult tissue homeostasis. Axin is a concentration-limiting factor responsible for the formation of the β-catenin destruction complex. Wnt signaling itself promotes the degradation of Axin. However, the underlying...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Ji, Lei, Jiang, Bo, Jiang, Xiaomo, Charlat, Olga, Chen, Amy, Mickanin, Craig, Bauer, Andreas, Xu, Wenqing, Yan, Xiaoxue, Cong, Feng
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458757/
https://ncbi.nlm.nih.gov/pubmed/28546513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.300053.117
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars