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Dab2 stabilizes Axin and attenuates Wnt/β-catenin signaling by preventing protein phosphatase 1 (PP1)–Axin interactions

Wnt/β-catenin signaling plays a pivotal role in modulating cellular proliferation, differentiation, tissue organization and embryonic development. Earlier, we found that the endocytic adaptor disabled-2 (Dab2) could attenuate Wnt/β-catenin signaling by stabilizing Axin and preventing its translocati...

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Detalhes bibliográficos
Main Authors: Jiang, Y, Luo, W, Howe, PH
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804437/
https://ncbi.nlm.nih.gov/pubmed/19581931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.157
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