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Dab2 stabilizes Axin and attenuates Wnt/β-catenin signaling by preventing protein phosphatase 1 (PP1)–Axin interactions
Wnt/β-catenin signaling plays a pivotal role in modulating cellular proliferation, differentiation, tissue organization and embryonic development. Earlier, we found that the endocytic adaptor disabled-2 (Dab2) could attenuate Wnt/β-catenin signaling by stabilizing Axin and preventing its translocati...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804437/ https://ncbi.nlm.nih.gov/pubmed/19581931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.157 |
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