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The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin

β-Catenin-mediated Wnt signaling is essential in embryonic development and in adult tissues. Recent studies have demonstrated that Axin not only plays an important inhibitory role in coordinating β-catenin degradation, but is itself degraded by the low-density-lipoprotein receptor-related protein (L...

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Detalhes bibliográficos
Main Authors: Jiang, Y, Prunier, C, Howe, PH
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810718/
https://ncbi.nlm.nih.gov/pubmed/17922036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210829
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