An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.

Most Borrelia burgdorferi strains have two major surface proteins, OspA and OspB. In the present study, we selected from a clonal population of infectious B. burgdorferi an OspB escape mutant, identified the genetic basis for this phenotype, and evaluated its functional activities. Selection with th...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Sadziene, A, Barbour, A G, Rosa, P A, Thomas, D D
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8359881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.9.3590-3596.1993
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