An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.

Most Borrelia burgdorferi strains have two major surface proteins, OspA and OspB. In the present study, we selected from a clonal population of infectious B. burgdorferi an OspB escape mutant, identified the genetic basis for this phenotype, and evaluated its functional activities. Selection with th...

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書誌詳細

出版年:	Infect Immun
主要な著者:	Sadziene, A, Barbour, A G, Rosa, P A, Thomas, D D
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1993
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8359881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.9.3590-3596.1993
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