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Inhibition of the Class C β-Lactamase from Acinetobacter spp: Insights into Effective Inhibitor Design
The need to develop β-lactamase inhibitors against class C cephalosporinases of Gram-negative pathogens represents an urgent clinical priority. To respond to this challenge, five boronic acid derivatives including a new cefoperazone analog were synthesized and tested against the class C cephalospori...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810401/ https://ncbi.nlm.nih.gov/pubmed/19925018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9015988 |
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