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Increased Matrix Metalloproteinase-9 Activity in Mild Cognitive Impairment

Nerve growth factor (NGF)-dependent cholinergic basal forebrain neurons degenerate during the progression of Alzheimer disease (AD). Elevated proNGF and reduced levels of the TrkA high-affinity NGF receptor occur in prodromal and advanced stages of AD. We recently described a protease cascade respon...

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Hlavní autoři: Bruno, Martin A., Mufson, Elliott J., Wuu, Joanne, Cuello, A. Claudio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810197/
https://ncbi.nlm.nih.gov/pubmed/19915485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181c22569
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