Noninvasive Imaging and Radiovirotherapy of Prostate Cancer Using an Oncolytic Measles Virus Expressing the Sodium Iodide Symporter

Prostate cancer cells overexpress the measles virus (MV) receptor CD46. Herein, we evaluated the antitumor activity of an oncolytic derivative of the MV Edmonston (MV-Edm) vaccine strain engineered to express the human sodium iodide symporter (NIS; MV-NIS virus). MV-NIS showed significant cytopathic...

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Autors principals: Msaouel, Pavlos, Iankov, Ianko D, Allen, Cory, Aderca, Ileana, Federspiel, Mark J, Tindall, Donald J, Morris, John C, Koutsilieris, Michael, Russell, Stephen J, Galanis, Evanthia
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810133/
https://ncbi.nlm.nih.gov/pubmed/19773744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.218
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