Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

Edmonston vaccine strains of measles virus (MV) have significant antitumor activity in mouse xenograft models of ovarian cancer. MV engineered to express the sodium iodide symporter gene (MV-NIS) facilitates localization of viral gene expression and offers a tool for tumor radiovirotherapy. Here, we...

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Vydáno v:Cancer Res
Hlavní autoři: Galanis, Evanthia, Atherton, Pamela J., Maurer, Matthew J., Knutson, Keith L., Dowdy, Sean C., Cliby, William A., Haluska, Paul, Long, Harry J., Oberg, Ann, Aderca, Ileana, Block, Matthew S., Bakkum-Gamez, Jamie, Federspiel, Mark J., Russell, Stephen J., Kalli, Kimberly R., Keeney, Gary, Peng, Kah Whye, Hartmann, Lynn C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377302/
https://ncbi.nlm.nih.gov/pubmed/25398436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2533
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