Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

Edmonston vaccine strains of measles virus (MV) have significant antitumor activity in mouse xenograft models of ovarian cancer. MV engineered to express the sodium iodide symporter gene (MV-NIS) facilitates localization of viral gene expression and offers a tool for tumor radiovirotherapy. Here, we...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Galanis, Evanthia, Atherton, Pamela J., Maurer, Matthew J., Knutson, Keith L., Dowdy, Sean C., Cliby, William A., Haluska, Paul, Long, Harry J., Oberg, Ann, Aderca, Ileana, Block, Matthew S., Bakkum-Gamez, Jamie, Federspiel, Mark J., Russell, Stephen J., Kalli, Kimberly R., Keeney, Gary, Peng, Kah Whye, Hartmann, Lynn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377302/
https://ncbi.nlm.nih.gov/pubmed/25398436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2533
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