Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

Edmonston vaccine strains of measles virus (MV) have significant antitumor activity in mouse xenograft models of ovarian cancer. MV engineered to express the sodium iodide symporter gene (MV-NIS) facilitates localization of viral gene expression and offers a tool for tumor radiovirotherapy. Here, we...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Galanis, Evanthia, Atherton, Pamela J., Maurer, Matthew J., Knutson, Keith L., Dowdy, Sean C., Cliby, William A., Haluska, Paul, Long, Harry J., Oberg, Ann, Aderca, Ileana, Block, Matthew S., Bakkum-Gamez, Jamie, Federspiel, Mark J., Russell, Stephen J., Kalli, Kimberly R., Keeney, Gary, Peng, Kah Whye, Hartmann, Lynn C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377302/
https://ncbi.nlm.nih.gov/pubmed/25398436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2533
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