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Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

Edmonston vaccine strains of measles virus (MV) have significant antitumor activity in mouse xenograft models of ovarian cancer. MV engineered to express the sodium iodide symporter gene (MV-NIS) facilitates localization of viral gene expression and offers a tool for tumor radiovirotherapy. Here, we...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Galanis, Evanthia, Atherton, Pamela J., Maurer, Matthew J., Knutson, Keith L., Dowdy, Sean C., Cliby, William A., Haluska, Paul, Long, Harry J., Oberg, Ann, Aderca, Ileana, Block, Matthew S., Bakkum-Gamez, Jamie, Federspiel, Mark J., Russell, Stephen J., Kalli, Kimberly R., Keeney, Gary, Peng, Kah Whye, Hartmann, Lynn C.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377302/
https://ncbi.nlm.nih.gov/pubmed/25398436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2533
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