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Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

Edmonston vaccine strains of measles virus (MV) have significant antitumor activity in mouse xenograft models of ovarian cancer. MV engineered to express the sodium iodide symporter gene (MV-NIS) facilitates localization of viral gene expression and offers a tool for tumor radiovirotherapy. Here, we...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Galanis, Evanthia, Atherton, Pamela J., Maurer, Matthew J., Knutson, Keith L., Dowdy, Sean C., Cliby, William A., Haluska, Paul, Long, Harry J., Oberg, Ann, Aderca, Ileana, Block, Matthew S., Bakkum-Gamez, Jamie, Federspiel, Mark J., Russell, Stephen J., Kalli, Kimberly R., Keeney, Gary, Peng, Kah Whye, Hartmann, Lynn C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377302/
https://ncbi.nlm.nih.gov/pubmed/25398436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2533
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