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Noninvasive Imaging and Radiovirotherapy of Prostate Cancer Using an Oncolytic Measles Virus Expressing the Sodium Iodide Symporter

Prostate cancer cells overexpress the measles virus (MV) receptor CD46. Herein, we evaluated the antitumor activity of an oncolytic derivative of the MV Edmonston (MV-Edm) vaccine strain engineered to express the human sodium iodide symporter (NIS; MV-NIS virus). MV-NIS showed significant cytopathic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Msaouel, Pavlos, Iankov, Ianko D, Allen, Cory, Aderca, Ileana, Federspiel, Mark J, Tindall, Donald J, Morris, John C, Koutsilieris, Michael, Russell, Stephen J, Galanis, Evanthia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810133/
https://ncbi.nlm.nih.gov/pubmed/19773744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.218
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