Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells

OBJECTIVE: Cytokines contribute to pancreatic β-cell death in type 1 diabetes. This effect is mediated by complex gene networks that remain to be characterized. We presently utilized array analysis to define the global expression pattern of genes, including spliced variants, modified by the cytokine...

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מידע ביבליוגרפי
Main Authors: Ortis, Fernanda, Naamane, Najib, Flamez, Daisy, Ladrière, Laurence, Moore, Fabrice, Cunha, Daniel A., Colli, Maikel L., Thykjaer, Thomas, Thorsen, Kasper, Ørntoft, Torben F., Eizirik, Decio L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Diabetes Association 2010
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809955/
https://ncbi.nlm.nih.gov/pubmed/19934004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1159
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