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In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells

BACKGROUND: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β and interferon (IFN)-γ. These cytokines modify the expression of hundreds of genes, leading to beta-cell dysfunction and dea...

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Detalhes bibliográficos
Main Authors: Naamane, Najib, van Helden, Jacques, Eizirik, Decio L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810323/
https://ncbi.nlm.nih.gov/pubmed/17302974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-55
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