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Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells
Although many eukaryotic proteins have been secreted by transfected bacterial cells, little is known about how a bacterial protein is treated as it passes through the secretory pathway when expressed in a eukaryotic cell. The eukaryotic N-glycosylation system could interfere with folding and secreti...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier Science Publishers
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2809921/ https://ncbi.nlm.nih.gov/pubmed/19900493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2009.11.002 |
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