DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis

OBJECTIVES: The influenza virus (IFV) infection models commonly used to evaluate antiviral agents (e.g. MDCK cell line and mice) are limited by physiological differences from the human respiratory tract in vivo. Here we report the pharmacodynamics of DAS181, a sialidase fusion protein that inhibits...

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Main Authors: Triana-Baltzer, Gallen B., Babizki, Maria, Chan, Michael C. W., Wong, Adam C. N., Aschenbrenner, Laura M., Campbell, Erin R., Li, Qi-Xiang, Chan, Renee W. Y., Peiris, J. S. Malik, Nicholls, John M., Fang, Fang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809246/
https://ncbi.nlm.nih.gov/pubmed/19942616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp421
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