Inhibition of Neuraminidase Inhibitor-Resistant Influenza Virus by DAS181, a Novel Sialidase Fusion Protein

Antiviral drug resistance for influenza therapies remains a concern due to the high prevalence of H1N1 2009 seasonal influenza isolates which display H274Y associated oseltamivir-resistance. Furthermore, the emergence of novel H1N1 raises the potential that additional reassortments can occur, result...

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Detalhes bibliográficos
Main Authors: Triana-Baltzer, Gallen B., Gubareva, Larisa V., Klimov, Alexander I., Wurtman, David F., Moss, Ronald B., Hedlund, Maria, Larson, Jeffrey L., Belshe, Robert B., Fang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770896/
https://ncbi.nlm.nih.gov/pubmed/19893749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007838
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