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Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181
BACKGROUND: Influenza viruses (IFVs) frequently achieve resistance to antiviral drugs, necessitating the development of compounds with novel mechanisms of action. DAS181 (Fludase(®)), a sialidase fusion protein, may have a reduced potential for generating drug resistance due to its novel host-target...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3001847/ https://ncbi.nlm.nih.gov/pubmed/21097900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq387 |
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