ICP0 Antagonizes ICP4-Dependent Silencing of the Herpes Simplex Virus ICP0 Gene

ICP0 is a regulatory protein that plays a critical role in the replication-latency balance of herpes simplex virus (HSV). Absence of ICP0 renders HSV prone to establish quiescent infections, and thus cellular repressor(s) are believed to silence HSV mRNA synthesis when ICP0 fails to accumulate. To d...

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Bibliografiske detaljer
Main Authors: Liu, Mingyu, Rakowski, Brandon, Gershburg, Edward, Weisend, Carla M., Lucas, Olivier, Schmidt, Edward E., Halford, William P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809113/
https://ncbi.nlm.nih.gov/pubmed/20098619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008837
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