ICP0 Antagonizes ICP4-Dependent Silencing of the Herpes Simplex Virus ICP0 Gene

ICP0 is a regulatory protein that plays a critical role in the replication-latency balance of herpes simplex virus (HSV). Absence of ICP0 renders HSV prone to establish quiescent infections, and thus cellular repressor(s) are believed to silence HSV mRNA synthesis when ICP0 fails to accumulate. To d...

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Detalhes bibliográficos
Main Authors: Liu, Mingyu, Rakowski, Brandon, Gershburg, Edward, Weisend, Carla M., Lucas, Olivier, Schmidt, Edward E., Halford, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809113/
https://ncbi.nlm.nih.gov/pubmed/20098619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008837
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