Minority Variants Associated with Transmitted and Acquired HIV-1 Non-Nucleoside RT Inhibitor (NNRTI) Resistance: Implications for the Use of Second Generation NNRTIs

OBJECTIVES: K103N, the most common nonnucleoside (NNRTI)-resistance mutation in patients with transmitted resistance and in patients receiving a failing NNRTI-containing regimen, is fully susceptible to the new NNRTI etravirine. Therefore, we sought to determine how often NNRTI-resistance mutations...

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Detalhes bibliográficos
Main Authors: Varghese, Vici, Shahriar, Rajin, Rhee, Soo-Yon, Liu, Tommy, Simen, Birgitte B., Egholm, Michael, Hanczaruk, Bozena, Blake, Lisbeth A., Gharizadeh, Baback, Babrzadeh, Farbod, Bachmann, Michael H., Fessel, W. Jeffrey, Shafer, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809083/
https://ncbi.nlm.nih.gov/pubmed/19734799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3181bca669
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