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Regulation of Fto/Ftm gene expression in mice and humans

Two recent, large GWAS in European populations have associated a ∼47 Kb region that contains part of the FTO gene with high BMI. The functions of FTO and adjacent FTM in human biology are not clear. We examined expression of these genes in organs of mice segregating for monogenic obesity mutations,...

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主要な著者: Stratigopoulos, George, Padilla, Stephanie, LeDuc, Charles A., Watson, Elizabeth, Hattersley, Andrew T., McCarthy, Mark I., Zeltser, Lori M., Chung, Wendy K., Leibel, Rudolph L.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808712/
https://ncbi.nlm.nih.gov/pubmed/18256137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00839.2007
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