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Regulation of Fto/Ftm gene expression in mice and humans

Two recent, large GWAS in European populations have associated a ∼47 Kb region that contains part of the FTO gene with high BMI. The functions of FTO and adjacent FTM in human biology are not clear. We examined expression of these genes in organs of mice segregating for monogenic obesity mutations,...

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Detalhes bibliográficos
Main Authors: Stratigopoulos, George, Padilla, Stephanie, LeDuc, Charles A., Watson, Elizabeth, Hattersley, Andrew T., McCarthy, Mark I., Zeltser, Lori M., Chung, Wendy K., Leibel, Rudolph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808712/
https://ncbi.nlm.nih.gov/pubmed/18256137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00839.2007
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