Hypomorphism of Fto and Rpgrip1l causes obesity in mice

Noncoding polymorphisms in the fat mass and obesity-associated (FTO) gene represent common alleles that are strongly associated with effects on food intake and adiposity in humans. Previous studies have suggested that the obesity-risk allele rs8050136 in the first intron of FTO alters a regulatory e...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Stratigopoulos, George, Burnett, Lisa Cole, Rausch, Richard, Gill, Richard, Penn, David Barth, Skowronski, Alicja A., LeDuc, Charles A., Lanzano, Anthony J., Zhang, Pumin, Storm, Daniel R., Egli, Dieter, Leibel, Rudolph L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855930/
https://ncbi.nlm.nih.gov/pubmed/27064284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85526
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