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PH-dependent Conformational Changes in Tear Lipocalin by Site Directed Tryptophan Fluorescence
Tear lipocalin (TL), a major protein of human tears, binds a broad array of endogenous ligands. PH-dependent ligand binding in TL may have functional implications in tears. Previously, conformational selections of the loops AB and GH have been implicated in ligand binding by site-directed tryptophan...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808433/ https://ncbi.nlm.nih.gov/pubmed/20025287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901435q |
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