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Tryptophan Rotamer Distribution Revealed for the Alpha-Helix in Tear Lipocalin by Site Directed Tryptophan Fluorescence

Rotamer libraries are a valuable tool for protein structure determination, modeling and design. Site-directed tryptophan fluorescence (SDTF) was used in combination with the rotamer model for the fluorescence intensity decays to solve α-helical conformations of proteins in solution. Single Trp mutat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gasymov, Oktay K., Abduragimov, Adil R., Glasgow, Ben J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517820/
https://ncbi.nlm.nih.gov/pubmed/23088798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp309318r
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