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Differences of globin transgene expression in stably transfected cell lines and transgenic mice
Previous studies demonstrated that DNase I hypersensitive site −40 (HS-40) of the α-globin locus is capable of greatly enhancing expression of a hybrid β/γ-globin transcriptional unit in plasmid-transfected murine erythroleukemia (MEL) cells. However, as reported here, this same γ-globin gene expres...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808413/ https://ncbi.nlm.nih.gov/pubmed/15626741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-03-0987 |
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