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Rab5 Mediates Caspase-8–promoted Cell Motility and Metastasis

Caspase-8 is a key apical sensory protein that governs cell responses to environmental cues, alternatively promoting apoptosis, proliferation, and cell migration. The proteins responsible for integration of these pathways, however, have remained elusive. Here, we reveal that Rab5 regulates caspase-8...

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Main Authors: Torres, Vicente A., Mielgo, Ainhoa, Barbero, Simone, Hsiao, Ruth, Wilkins, John A., Stupack, Dwayne G.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808229/
https://ncbi.nlm.nih.gov/pubmed/19923319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0769
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