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Rab5 Mediates Caspase-8–promoted Cell Motility and Metastasis

Caspase-8 is a key apical sensory protein that governs cell responses to environmental cues, alternatively promoting apoptosis, proliferation, and cell migration. The proteins responsible for integration of these pathways, however, have remained elusive. Here, we reveal that Rab5 regulates caspase-8...

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Detalles Bibliográficos
Main Authors: Torres, Vicente A., Mielgo, Ainhoa, Barbero, Simone, Hsiao, Ruth, Wilkins, John A., Stupack, Dwayne G.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808229/
https://ncbi.nlm.nih.gov/pubmed/19923319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0769
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