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Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein

Seasonal epidemics and periodic worldwide pandemics caused by influenza A viruses are of continuous concern. The viral nonstructural (NS1) protein is a multifunctional virulence factor that antagonizes several host innate immune defenses during infection. NS1 also directly stimulates class IA phosph...

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Detalhes bibliográficos
Main Authors: Hale, Benjamin G., Kerry, Philip S., Jackson, David, Precious, Bernard L., Gray, Alexander, Killip, Marian J., Randall, Richard E., Russell, Rupert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808220/
https://ncbi.nlm.nih.gov/pubmed/20133840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910715107
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