Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling

Influenza A virus NS1 is a multifunctional protein, and in virus-infected cells NS1 modulates a number of host-cell processes by interacting with cellular factors. Here, we report that NS1 binds directly to p85β, a regulatory subunit of phosphatidylinositol-3-kinase (PI3K), but not to the related p8...

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Main Authors: Hale, Benjamin G., Jackson, David, Chen, Yun-Hsiang, Lamb, Robert A., Randall, Richard E.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599933/
https://ncbi.nlm.nih.gov/pubmed/16963558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606109103
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