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Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone β receptor

Activation of the phosphatidylinositol 3-kinase (PI3K)–AKT/protein kinase B signaling pathway has been associated with multiple human cancers. Recently we showed that AKT is activated in both the thyroid and metastatic lesions of a mouse model of follicular thyroid carcinoma [thyroid hormone β recep...

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Detalhes bibliográficos
Main Authors: Furuya, Fumihiko, Hanover, John A., Cheng, Sheue-yann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413672/
https://ncbi.nlm.nih.gov/pubmed/16446424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510849103
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