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Novel functions of thyroid hormone receptor mutants: Beyond nucleus-initiated transcription
Study of molecular actions of thyroid hormone receptor β (TRβ) mutants in vivo has been facilitated by creation of a mouse model (TRβPV mouse) that harbors a knockin mutant of TRβ (denoted PV). PV, which was identified in a patient with resistance to thyroid hormone, has lost T3 binding activity and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794798/ https://ncbi.nlm.nih.gov/pubmed/17169389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2006.11.005 |
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