Iron-Dependent Regulation of MDM2 Influences p53 Activity and Hepatic Carcinogenesis

Iron overload is a risk factor for hepatocarcinoma, but the pathways involved are poorly characterized. Gene expression analysis in immortalized mouse hepatocytes exposed to iron or the iron chelator deferoxamine revealed that iron downregulated, whereas deferoxamine upregulated, mRNA levels of mous...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dongiovanni, Paola, Fracanzani, Anna Ludovica, Cairo, Gaetano, Megazzini, Chiara Paola, Gatti, Stefano, Rametta, Raffaela, Fargion, Silvia, Valenti, Luca
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2010
Aiheet:
Regular Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808103/
https://ncbi.nlm.nih.gov/pubmed/20019189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090249
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia