Prognostic Significance of Gremlin1 (GREM1) Promoter CpG Island Hypermethylation in Clear Cell Renal Cell Carcinoma

Gremlin1 (GREM1), a bone morphogenetic protein antagonist and putative angiogenesis-modulating gene, is silenced by promoter hypermethylation in human malignancies. Here we study GREM1 methylation in clear cell renal cell carcinoma (ccRCC) and its impact on tumor characteristics and clinical outcome...

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Detaylı Bibliyografya
Asıl Yazarlar: van Vlodrop, Iris J.H., Baldewijns, Marcella M.L., Smits, Kim M., Schouten, Leo J., van Neste, Leander, van Criekinge, Wim, van Poppel, Hein, Lerut, Evelyne, Schuebel, Kornel E., Ahuja, Nita, Herman, James G., de Bruïne, Adriaan P., van Engeland, Manon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2010
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808066/
https://ncbi.nlm.nih.gov/pubmed/20042676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090442
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