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Development Of Foxp3(+) Regulatory T Cells Is Driven By A c-Rel Enhanceosome
Regulatory T (Treg) cells play essential roles in maintaining immune homeostasis. While Foxp3 expression marks the commitment of progenitors to Treg lineage, how Treg cells are generated during lymphocyte development remains enigmatic. Both NFAT and Smad have been implicated in Foxp3 gene activation...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807990/ https://ncbi.nlm.nih.gov/pubmed/20064450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.10.006 |
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