Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

BACKGROUND: The Fanconi anemia (FA) pathway is a multigene DNA damage response network implicated in the repair of DNA lesions that arise during replication or after exogenous DNA damage. The FA pathway displays synthetic lethal relationship with certain DNA repair genes such as ATM (Ataxia Telangec...

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Détails bibliographiques
Auteurs principaux: Landais, Igor, Hiddingh, Sanne, McCarroll, Matthew, Yang, Chao, Sun, Aiming, Turker, Mitchell S, Snyder, James P, Hoatlin, Maureen E
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807854/
https://ncbi.nlm.nih.gov/pubmed/20043851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-133
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