Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

BACKGROUND: The Fanconi anemia (FA) pathway is a multigene DNA damage response network implicated in the repair of DNA lesions that arise during replication or after exogenous DNA damage. The FA pathway displays synthetic lethal relationship with certain DNA repair genes such as ATM (Ataxia Telangec...

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Detalhes bibliográficos
Main Authors: Landais, Igor, Hiddingh, Sanne, McCarroll, Matthew, Yang, Chao, Sun, Aiming, Turker, Mitchell S, Snyder, James P, Hoatlin, Maureen E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807854/
https://ncbi.nlm.nih.gov/pubmed/20043851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-133
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